Understanding Cancer Cell Communication

to Infer a Strategy to Inhibit Tumor Cell Migration

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Denis Wirtz, PhD, Vice Provost for Research Director, Johns Hopkins Physical Sciences-Oncology Center Johns Hopkins University and Johns Hopkins School of Medicine
  • How cell density and proliferation affect tumor cell metastasis and how they shape the development of novel therapies

  • How cytokine profiling and highly multiplexed proteomic analysis of three-dimensional models help identify proteins encouraging cell migration

  • How identifying a potential mechanism promoting tumor cell migration enables the development of a strategy to decrease tumor cell metastatic capacity