IsoPlexis is empowering the ability to accelerate discovery of immune cell impacts on vaccine & immunology research
By finding the small groups of potent immune cells that are driving response, IsoPlexis is working with leaders to address challenges across disease types that can be addressed with improved understanding of potency, durability and dysfunction earlier in the development process.
Vaccines & Immunology Research
Join us to learn more about how we are accelerating vaccine & immunology related programs across the discover-optimize-predict continuum with our unique cellular analysis metrics
IsoPlexis' systems reveal differences in cancer vaccines tested on humanized mice, which enable choice
Our products are uncovering the T cell mechanism of malaria vaccines administered to mice, correlated to survival
Our systems have stratified patients in immune monitoring for cancer vaccines, using single-cell polyfunction
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Single-Cell Highly Multiplexed Proteomics Identifies Novel Polyfunctional Human CD8+ T Cell Signatures Induced by a Nanoparticle-Based Melanoma Vaccine in Human Immune System Mice. Mackay S, Morse K, Paczkowski P, Huang J, Tsuji M, and Zhou J. Presented at FOCiS Annual Meeting 2018.
CD8+ T-Cell Mediated Anti-Malaria Protection Induced by Malaria Vaccines; Assessment of Hepatic CD8+ T Cells by SCBC Assay. Zhou J, Kaiser A, Ng C, Karcher R, McConnell T, Paczkowski P, Fernandez C, Zhang M, Mackay S, and Tsuji M. Human Vaccines & Immunotherapeutics, 13 (7), 1625-1629 (2017).
Single-Cell Polyfunctionality of CD4+ T Cells Shows Promise as a Predictor of Overall Survival of Pancreatic Cancer Patients Treated with GVAX Vaccine. Mackay S, Flynn B, Chen J, Paczkowski P, Jaffee E, Zheng L, and Zhou J. Presented at FOCiS Annual Meeting 2018.