Capture key measures of potency & durability that correlate with outcome
Our Award-Winning Single-Cell Polyfunctional Strength System (IsoLight) detects the most potent cell subsets by analyzing the ability of each cell to secrete multiple cytokines simultaneously at high intensity.
The IsoLight then automatically translates this data into insight, generating a unique metric (PSI™), that helps researchers understand the potency and durability that correlate to in-vivo activity.
In the fight against cancer,
each cell makes a difference.
In preclinical development, it is critical to identify the complex immunotherapies and combinations that will be most effective in combating the tumor early.
IsoPlexis’ unique single cell systems have uncovered the potent subsets of these immune cells that have correlated uniquely with in vivo response to cancer therapies, both in human and in mice.
IsoPlexis’ system connects over 30 cytokines that orchestrate the immune response from each T cell, back to the cell itself.
- Our chip measures the range of 32 cytokines that orchestrate the T-cell response in immunotherapy
- This panel is measured from each of 1000+ single cells
- The most potent cells that secrete multiple cytokines at high intensities, i.e. polyfunctional cells, are captured uniquely