Adaptive Immune

Human / Mouse

A fully automated solution for single-cell functional phenotyping of immune cells

IsoCode Technology

Existing customer?

The New Standard in
Single-Cell Functional Biology

The IsoLight is a hub for comprehensive functional profiling of each cell type across a large assay menu of single-cell chip and software products. Run an entire highly-multiplexed proteomics workflow. Just add your sample and walk away, achieving fully analyzed data on the same day.

32+ Cytokine Analysis

Multiplexed 32+ cytokine analysis at single-cell resolution

isoplexis barcode
Functional Phenotyping

Functional Phenotyping targeting 500-1500 single cells per chip

Fully Automated

Fully automated, quick, and cost-efficient workflow

technology workflow
IsoPlexis' Innovation in Cellular Analysis: the IsoCode Chip

Our proprietary & patented “Proteomic Barcoded” IsoCode Chip, named the Scientist’s number #1 innovation, works by detecting 30+ cytokines per cell, measuring the functional phenotype of each immune cell.

Cytokine Panel
  • Effector

    Granzyme B, IFN-γ, MIP-1α, Perforin, TNF-α, TNF-β

  • Stimulatory

    GM-CSF, IL-2, IL-5, IL-7, IL-8, IL-9, IL-12, IL-15, IL-21

  • Chemoattractive

    CCL11, IP-10, MIP-1β, RANTES

  • Regulatory

    IL-4, IL-10, IL-13, IL-22, TGFβ1, sCD137, sCD40L

  • Inflammatory

    IL-1β, IL-6, IL-17A, IL-17F, MCP-1, MCP-4

Cytokine Panel

GM-CSF, IFN-g, IL-12p70, IL-1b, IL-2, IL-4, IL-6, IL-8, IP-10, MCP-1, MIF, MIP-1a, RANTES, TNF-a

Cytokine Panel
  • Effector

    Granzyme B, IFN-γ, MIP-1α, TNF-α

  • Stimulatory

    GM-CSF, IL-2, IL-5, IL-7, IL-12p70, IL-15, IL-18, IL-21, sCD137

  • Chemoattractive

    CCL11, CXCL1, CXCL13, IP-10, RANTES

  • Regulatory

    Fas, IL-4, IL-10, IL-13, IL-27, TGFβ1

  • Inflammatory

    IL-6, IL-17A, MCP-1, IL-1β

Subset Panels
  • Membrane Stain
  • Memory T cell subsets
Single-Cell Adaptive Immune
A Breakthrough
Technological Innovation

The Single-Cell Adaptive Immune solution measures the “functional phenotype” of each immune cell, allowing for complete single-cell functional characterization. This enables researchers to detect how immune cells proteomically perform against a heterogeneous system, revealing functional biological drivers of persistence, potency, durability and more.

Case Studies & Research
Support and Continued Learning
IsoPlexis University

Protocol Training Videos, Manuals, Support Literature

Workflow & Support

Project Guides, Checklists, and Protocols

Product Specifications
IsoLight System ISOLIGHT-1000-1
IsoSpeak Software ISOSPEAK-1000-1
IsoCode Chips - 4 ISOCODE-1000-4
IsoCode Chips - 6 ISOCODE-1000-6
IsoCode Chips - 8 ISOCODE-1000-8
Single-Cell Adaptive Immune Panel (human) – 4 PANEL-1001-4
Single-Cell Adaptive Immune Panel (human) – 6 PANEL-1001-6
Single-Cell Adaptive Immune Panel (human) – 8 PANEL-1001-8
Single-Cell Adaptive Immune Panel (mouse) – 4 PANEL-1004-4
Single-Cell Adaptive Immune Panel (mouse) – 6 PANEL-1004-6
Single-Cell Adaptive Immune Panel (mouse) – 8 PANEL-1004-8
Stain Cell Membrane 405 STAIN-1001-1
Stain CD4-647 STAIN-1002-1
Stain CD8-647 STAIN-1003-1
Stain CD45RO-APC STAIN-1004-1
Single-Cell Adaptive Immune
IsoCode is Part of the
Proteomic Hub Workflow
ONE INSTRUMENT & Workflow Step
The IsoLight
Data visualization software
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The single-use IsoCode chips are at the core of our technology and required to run our single-cell profiling assays on the fully automated and Award-Winning IsoLight System.

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