IsoPlexis’ CodePlex solution is uniquely capturing key measures of multiplexed bulk cytokine metrics in an automated manner

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CodePlex Technology

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The New Standard in
Functional Biology

IsoPlexis’ CodePlex solution is helping researchers by providing a faster and more streamlined approach to generating multiplexed bulk cytokine data via a fully automated end-to-end workflow. It does this by offering a modular solution to bulk cytokine data analysis and minimizes variability from user input.

Automated Highly Multiplexed Proteomics Workflow
10X improvement over status quo
Easily Run Limited Sample Volumes

Sample volume needed for replicates on CodePlex Secretome


Sample volume needed for replicates on Status Quo Instrumentation

Only 5 Min of Hands-on Time

Step 1:
One-pipette-action per sample, no ELISA procedures by user

Step 2:
All ELISA procedures performed automatically. Software delivers results.

Save Time, Less Cost
  • Optimize your workflow with only 5 min hands-on time

  • CodePlex family of chips runs can generate same-day data, completely automated

  • One IsoLight system as a hub for single-cell and population proteomic analysis.

IsoLight One Instrument Worfklow
IsoLight Steps For Functional Immune Profiling
Completely Automated for the First Time
  • 1 System: Imaging, Incubation, Washing, ELISA

  • Target 30+ Cytokines: Single-Cell & Population Proteomics

  • Many: Chip Products, Panels, and Cell types

Panel Menu

Granzyme B, IFN-y, MIP-1a, Perforin, TNF-a, TNF-B, GM-CSF, IL-2, IL-5, IL-7, IL-8, IL-9, IL-12, IL-15, IL-21, CCL11, IP-10, MIP-1B, RANTES, IL-4, IL-10, IL-13, IL-22, TGF-B1, sCD137, sCD40L, IL-1B, IL-6, IL-17a, IL17F, MCP1, MCP-4, IL-18, TGF-a, BCA-1, IL-12-p40, MIF, EGF, PDGF-BB, VEGF

Human Adaptive Immune

IL-17A, TGF-b1, MIP-1a, IL-9, MIP-1b, IL-6, IL-7, IL-8, IFN-y, IP-10, GM-CSF, IL-4, IL-5, IL-10, TNF-a, MCP-1, IL-13, IL-2, Perforin, sCD137, TNF-b, Granzyme B, IL-15

Human Cytokine Storm Panel

IL-1b, IL-2, IL-4, IL-6, IL-7, IL-10, IL-12, IL-13, IL-17, MCP-1, GM-CSF, MIP-1a, MIP-1b, TNF-a, IFN-y

Human Innate Immune - Coming Soon

IL-17A, TGF-b1, MIP-1a, MIP-1b, IL-6, IL-7, IL-8, IFN-y, IP-10, GM-CSF, IL-4, IL-5, IL-10, TNF-a, MCP-1, IL-2, Perforin, sCD40L,  sCD137, TNF-b, Granzyme B, IL-15, PDGF-BB

Cancer Signaling - Coming Soon

IL-6,  IL-7, IFN-y, IL-4, IL-5, IL-10, TNF-a, MCP-1, IL-13, IL-2, EGF, PDGF-BB, VEGF, Rantes (MPN), MIF, FGF, HGF, IL1a, IL1b, IL12

Stem Cell Signaling - Coming Soon

IL-17A, TGF-b1, MIP-1a, MIP-1b, IL-6, IL-8, IFN-y, GM-CSF, IL-4, IL-10, TNF-a, MCP-1, IL-2, IL-15, Rantes (MPN), IL1a, IL1b, IL12, CCL2, CXCL5 * (MPN)

A Breakthrough
Technological Innovation

The CodePlex Secretome chips are used to optimize experimental conditions by enabling quick and cost-efficient population assays. The CodePlex Secretome Immuno-Oncology Panel measures 32+ cytokines in bulk, automated on the IsoLight system, and can selectively run 8 conditions a chip in “MacroChambers” across 8 chips on a single run. 

Tech Specs
Up to 100-200 uL per sample (for replicates)
6-10 hours of hands-on sample prep time
Workflow requires multiple steps and user interaction points
Fill 96 samples before run
Multiple systems required to generate and analyze data
Limit of Detection: 5-5000 pg/ml
Data analysis & visualization requires manual user input
11 uL per samples (for replicates)
5 minutes of hands-on time
Completely automated workflow
Modular, load 8-64 samples per run
One system: The IsoLight
Limit of Detection: 5-5000 pg/ml
State-of-the-art data analysis software with advanced visualizations
Case Studies & Research
Support and Continued Learning
IsoPlexis University

Protocol Training Videos, Manuals, Support Literature

Workflow & Support

Project Guides, Checklists, and Protocols

Product Specifications
IsoLight System ISOLIGHT-1000-1
IsoSpeak Software ISOSPEAK-1000-1
CodePlex Chips – 1 CODEPLEX-2000-1
CodePlex Chips – 2 CODEPLEX-2000-2
CodePlex Chips – 4 CODEPLEX-2000-4
CodePlex Chips – 6 CODEPLEX-2000-6
CodePlex Chips – 8 CODEPLEX-2000-8
CodePlex Human Adaptive Immune-L Panel - 1 PANEL-2L01-1
CodePlex Human Adaptive Immune-L Panel - 2 PANEL-2L01-2
CodePlex Human Adaptive Immune-L Panel - 4 PANEL-2L01-4
CodePlex Human Adaptive Immune-L Panel - 6 PANEL-2L01-6
CodePlex Human Adaptive Immune-L Panel - 8 PANEL-2L01-8
CodePlex Human Cytokine Storm-L Panel - 1 PANEL-2L02-1
CodePlex Human Cytokine Storm-L Panel - 2 PANEL-2L02-2
CodePlex Human Cytokine Storm-L Panel - 4 PANEL-2L02-4
CodePlex Human Cytokine Storm-L Panel - 6 PANEL-2L02-6
CodePlex Human Cytokine Storm-L Panel - 8 PANEL-2L02-8
IsoLight Service Agreement - 1 Year SVCISL-1000-1
IsoLight Service Agreement - 2 Year SVCISL-1000-2
CodePlex is Part of the
Proteomic Hub Workflow
ONE INSTRUMENT & Workflow Step
The IsoLight
Data visualization software
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The single-use CodePlex chips are at the core of our technology and required to run our profiling assays on the fully automated and Award-Winning IsoLight System.

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