Codeplex

CodePlex

IsoPlexis’ CodePlex solution is uniquely capturing key measures of multiplexed bulk cytokine metrics in an automated manner

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OVERVIEW
The New Standard in
Functional Biology

IsoPlexis’ CodePlex solution is helping researchers by providing a faster and more streamlined approach to generating multiplexed bulk cytokine data via a fully automated end-to-end workflow. It does this by offering a modular solution to bulk cytokine data analysis and minimizes variability from user input.

Featured Resource

CodePlex Secretome
Product Sheet

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CODEPLEX SECRETOME
Automated Highly Multiplexed Proteomics Workflow
10X improvement over status quo
Easily Run Limited Sample Volumes
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Sample volume needed for replicates on CodePlex

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Sample volume needed for replicates on Status Quo Instrumentation

CODEPLEX SECRETOME
Only 5 Min of Hands-on Time

Step 1:
One-pipette-action per sample, no ELISA procedures by user

Step 2:
All ELISA procedures performed automatically. Software delivers results.

Save Time, Less Cost

  • Optimize your workflow with only 5 min hands-on time

  • CodePlex family of chips runs can generate same-day data, completely automated

  • One IsoLight system as a hub for single-cell and population proteomic analysis.

IsoLight One Instrument Worfklow
IsoLight Steps For Functional Immune Profiling
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Completely Automated for the First Time

  • 1 System: Imaging, Incubation, Washing, ELISA

  • Target 30+ Cytokines: Single-Cell & Population Proteomics

  • Many: Chip Products, Panels, and Cell types

Human Stem Cell Signaling

IL-17A, MIP-1α, IL-6, IL-4, MIP-1β, IL-8, IFN-γ, GM-CSF, IL-10, TNF-α, MCP-1, IL-2, IL-15, RANTES, IL-1α, IL-1β, CXCL5

Human Cancer Signaling

EGF, IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-13, MCP-1, MIF, PDGF-BB, RANTES, TNF-α

Mouse Inflammation

IFN-γ, TNF-α, MIP-1α, IL-2, IL-5, IL-10, IL-13, IL-4, IL-6, IL-1β, IL-17A, IL-12, MCP-1, IP-10, KC, GM-CSF

Mouse Innate Immune

IFN-γ, TNF-α, MIP-1α, IL-15, GM-CSF, IL-5, IL-10, IL-13, IL-6, IL-17A, MCP-1, IP-10, MIP-1β, EGF, PDGF-BB, MIF

Mouse Stem Cell Signaling - in pipeline

GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-10, IL-15, IL-17A, MCP-1, MIP-1α, MIP-1β, RANTES, TNF-α

Mouse Cancer Signaling - in pipeline

EGF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-13, MCP-1, MIF, PDGF-BB, RANTES, TNF-α, VEGF

Panel Menu

CXCL5, EGF, GM-CSF, Granzyme B, IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-13, IL-15, IL-17A, IP-10, KC, MCP-1, MIF, MIP-1α, MIP-1β, PDGF-BB, Perforin, RANTES, sCD137, TNF-α, TNF-β, VEGF

Human Adaptive Immune

GM-CSF, Granzyme B, IFN-γ, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-13, IL-15, IL-17A, IP-10, MCP-1, MIP-1α, MIP-1β, Perforin, sCD137, TNF-α, TNF-β

Mouse Adaptive Immune

GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-17A, IP-10, KC, MCP-1, MIP-1α, RANTES, TNF-α

Human Cytokine Storm

GM-CSF, IFN-γ, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-13, IL-17A, IP-10, MCP-1, MIP-1α, MIP-1β, Perforin, TNF-α

Non-Human Primate Adaptive Immune

GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-8, IP-10, MCP-1, MIP-1α, MIP-1β, RANTES, TNF-α

Human Innate Immune

EGF, GM-CSF, Granzyme B, IFN-γ, IL-1β, IL-4, IL-6, IL-7, IL-8, IL-10, IL-15, IP-10, MCP-1, MIP-1α, MIP-1β, PDGF-BB, sCD137, TNF-α, VEGF

Human Tumor Signaling - in pipeline

P-PRAS40, P-IkBα, P-NF-kβ p65, P-Met, P-p44/42 MAPK, P-S6 Ribosomal, P-p90RSK, P-STAT3, P-MEK1/2, P-Stat1, P-Stat5, P-eIF4E, Cleaved PARP, Alpha Tubulin

CODEPLEX
A Breakthrough
Technological Innovation

The CodePlex chips are used to optimize experimental conditions by enabling quick and cost-efficient population assays. The CodePlex Adaptive Immune Panel measures 32+ cytokines in bulk, automated on the IsoLight or IsoSpark system, and can selectively run 8 conditions a chip in “MacroChambers” across 8 chips on the IsoLight or 4 chips on the IsoSpark on a single run. 

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Our Unique Biology
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Tech Specs
Up to 100-200 uL per sample (for replicates)
6-10 hours of hands-on sample prep time
Workflow requires multiple steps and user interaction points
Fill 96 samples before run
Multiple systems required to generate and analyze data
Limit of Detection: 5-5000 pg/ml
Data analysis & visualization requires manual user input
11 uL per samples (for replicates)
5 minutes of hands-on time
Completely automated workflow
Modular, load 8-64 samples per run
One system: The IsoLight
Limit of Detection: 5-5000 pg/ml
State-of-the-art data analysis software with advanced visualizations
Case Studies & Research
Data
Featured Case Study
Understanding Cell Communication to Infer a Strategy to Inhibit Tumor Cell Migration
Paper Summary
Immune-cell Functional Profiling Sheds Light on the Pathogenesis of Severe COVID-19
App Note
Key Functional Insights Uncovered with CodePlex High-Plex Low Volume Immunoassays
Case Study
Understanding Cell Communication to Infer a Strategy to Inhibit Tumor Cell Migration
Support and Continued Learning
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IsoPlexis University

Protocol Training Videos, Manuals, Support Literature

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Workflow & Support

Project Guides, Checklists, and Protocols

Product Specifications
Codeplex Loading Training Chip CODEPLEX-2100-1
CodePlex Adaptive Immune Chip – (H) 1 CODEPLEX-2L01-1
CodePlex Adaptive Immune Chip – (H) 2 CODEPLEX-2L01-2
CodePlex Adaptive Immune Chip – (H) 4 CODEPLEX-2L01-4
CodePlex Adaptive Immune Chip – (H) 6 CODEPLEX-2L01-6
CodePlex Adaptive Immune Chip – (H) 8 CODEPLEX-2L01-8
CodePlex Adaptive Immune Chip – (M) 1 CODEPLEX-2L04-1
CodePlex Adaptive Immune Chip – (M) 2 CODEPLEX-2L04-2
CodePlex Adaptive Immune Chip – (M) 4 CODEPLEX-2L04-4
CodePlex Adaptive Immune Chip – (M) 6 CODEPLEX-2L04-6
CodePlex Adaptive Immune Chip – (M) 8 CODEPLEX-2L04-8
CodePlex Adaptive Immune Chip – (NHP) 1 CODEPLEX-2L09-1
CodePlex Adaptive Immune Chip – (NHP) 2 CODEPLEX-2L09-2
CodePlex Adaptive Immune Chip – (NHP) 4 CODEPLEX-2L09-4
CodePlex Adaptive Immune Chip – (NHP) 6 CODEPLEX-2L09-6
CodePlex Adaptive Immune Chip – (NHP) 8 CODEPLEX-2L09-8
CodePlex Innate Immune Chip – (H) 1 CODEPLEX-2L03-1
CodePlex Innate Immune Chip – (H) 2 CODEPLEX-2L03-2
CodePlex Innate Immune Chip – (H) 4 CODEPLEX-2L03-4
CodePlex Innate Immune Chip – (H) 6 CODEPLEX-2L03-6
CodePlex Innate Immune Chip – (H) 8 CODEPLEX-2L03-8
CodePlex Cytokine Storm Chip – (H) 1 CODEPLEX-2L02-1
CodePlex Cytokine Storm Chip – (H) 2 CODEPLEX-2L02-2
CodePlex Cytokine Storm Chip – (H) 4 CODEPLEX-2L02-4
CodePlex Cytokine Storm Chip – (H) 6 CODEPLEX-2L02-6
CodePlex Cytokine Storm Chip – (H) 8 CODEPLEX-2L02-8
CodePlex Adaptive Immune Panel – (H) 1 PANEL-2L01-1
CodePlex Adaptive Immune Panel – (H) 2 PANEL-2L01-2
CodePlex Adaptive Immune Panel – (H) 4 PANEL-2L01-4
CodePlex Adaptive Immune Panel – (H) 6 PANEL-2L01-6
CodePlex Adaptive Immune Panel – (H) 8 PANEL-2L01-8
CodePlex Adaptive Immune Panel – (M) 1 PANEL-2L04-1
CodePlex Adaptive Immune Panel – (M) 2 PANEL-2L04-2
CodePlex Adaptive Immune Panel – (M) 4 PANEL-2L04-4
CodePlex Adaptive Immune Panel – (M) 6 PANEL-2L04-6
CodePlex Adaptive Immune Panel – (M) 8 PANEL-2L04-8
CodePlex Adaptive Immune Panel – (NHP) 1 PANEL-2L09-1
CodePlex Adaptive Immune Panel – (NHP) 2 PANEL-2L09-2
CodePlex Adaptive Immune Panel – (NHP) 4 PANEL-2L09-4
CodePlex Adaptive Immune Panel – (NHP) 6 PANEL-2L09-6
CodePlex Adaptive Immune Panel – (NHP) 8 PANEL-2L09-8
CodePlex Innate Immune Panel – (H) 1 PANEL-2L03-1
CodePlex Innate Immune Panel – (H) 2 PANEL-2L03-2
CodePlex Innate Immune Panel – (H) 4 PANEL-2L03-4
CodePlex Innate Immune Panel – (H) 6 PANEL-2L03-6
CodePlex Innate Immune Panel – (H) 8 PANEL-2L03-8
CodePlex Cytokine Storm Panel – (H) 1 PANEL-2L02-1
CodePlex Cytokine Storm Panel – (H) 2 PANEL-2L02-2
CodePlex Cytokine Storm Panel – (H) 4 PANEL-2L02-4
CodePlex Cytokine Storm Panel – (H) 6 PANEL-2L02-6
CodePlex Cytokine Storm Panel – (H) 8 PANEL-2L02-8
Codeplex Loading Training Chip CODEPLEX-2100-1
CodePlex Adaptive Immune Chip – (H) 1 CODEPLEX-2L01-1
CodePlex Adaptive Immune Chip – (H) 2 CODEPLEX-2L01-2
CodePlex Adaptive Immune Chip – (H) 4 CODEPLEX-2L01-4
CodePlex Adaptive Immune Chip – (M) 1 CODEPLEX-2L04-1
CodePlex Adaptive Immune Chip – (M) 2 CODEPLEX-2L04-2
CodePlex Adaptive Immune Chip – (M) 4 CODEPLEX-2L04-4
CodePlex Adaptive Immune Chip – (NHP) 1 CODEPLEX-2L09-1
CodePlex Adaptive Immune Chip – (NHP) 2 CODEPLEX-2L09-2
CodePlex Adaptive Immune Chip – (NHP) 4 CODEPLEX-2L09-4
CodePlex Innate Immune Chip – (H) 1 CODEPLEX-2L03-1
CodePlex Innate Immune Chip – (H) 2 CODEPLEX-2L03-2
CodePlex Innate Immune Chip – (H) 4 CODEPLEX-2L03-4
CodePlex Cytokine Storm Chip – (H) 1 CODEPLEX-2L02-1
CodePlex Cytokine Storm Chip – (H) 2 CODEPLEX-2L02-2
CodePlex Cytokine Storm Chip – (H) 4 CODEPLEX-2L02-4
CodePlex Adaptive Immune Panel – (H) 1 S-PANEL-2L01-1
CodePlex Adaptive Immune Panel – (H) 2 S-PANEL-2L01-2
CodePlex Adaptive Immune Panel – (H) 4 S-PANEL-2L01-4
CodePlex Adaptive Immune Panel – (M) 1 S-PANEL-2L04-1
CodePlex Adaptive Immune Panel – (M) 2 S-PANEL-2L04-2
CodePlex Adaptive Immune Panel – (M) 4 S-PANEL-2L04-4
CodePlex Adaptive Immune Panel – (NHP) 1 S-PANEL-2L09-1
CodePlex Adaptive Immune Panel – (NHP) 2 S-PANEL-2L09-2
CodePlex Adaptive Immune Panel – (NHP) 4 S-PANEL-2L09-4
CodePlex Innate Immune Panel – (H) 1 S-PANEL-2L03-1
CodePlex Innate Immune Panel – (H) 2 S-PANEL-2L03-2
CodePlex Innate Immune Panel – (H) 4 S-PANEL-2L03-4
CodePlex Cytokine Storm Panel – (H) 1 S-PANEL-2L02-1
CodePlex Cytokine Storm Panel – (H) 2 S-PANEL-2L02-2
CodePlex Cytokine Storm Panel – (H) 4 S-PANEL-2L02-4
RESEARCH AREAS
IsoPlexis is Accelerating Breakthroughs: See Where
CODEPLEX SECRETOME
CodePlex is Part of the
Proteomic Hub Workflow
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ONE INSTRUMENT & Workflow Step
The IsoLight
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Data visualization software
IsoSpeak
GET STARTED
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The single-use CodePlex chips are at the core of our technology and required to run our profiling assays on the fully automated and Award-Winning IsoLight System.

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