Energy State Technology
Single-Cell Functional Biology
The IsoLight and IsoSpark instruments are hubs for comprehensive functional profiling of each cell type across a large assay menu of single-cell chip and software products. Run an entire highly-multiplexed proteomics workflow. Just add your sample and walk away, achieving fully analyzed data on the same day.
Highly multiplexed metabolomics analysis at single-cell resolution
Functional Phenotyping targeting 500-1500 single cells per chip
Fully automated, quick, and cost-efficient workflow
Our proprietary & patented “Proteomic Barcoded” IsoCode Chip, captures single cells in each microchamber, and detects metabolites and functional proteins, enabling predictive intracellular discoveries.
Human Tumor Metabolome - Coming Soon
P-PRAS40, P-IkBα, P-NF-kβ p65, P-Met, P-p44/42 MAPK, P-S6 Ribosomal, P-Rb, P-p90RSK, P-Stat3, P-MEK1/2, P-Stat1, P-Stat5, P-eIF4E, Cleaved PARP, Alpha Tubulin, Glucose-Biotin
IsoPlexis’ multi-omics (metabolomics + functional proteomics) provide a critical and uniquely capable tool for addressing functional and metabolic changes that accompany adaptive resistance development. Through the use of IsoPlexis’ multiomic energy state application, independent trajectories to drug tolerance can be revealed, enabling researchers to better develop combination therapies to combat this drug-resistant cell state and prevent drug resistance.
The single-use IsoCode chips are at the core of our technology and required to run our profiling assays on the fully automated and Award-Winning IsoLight System.
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