IsoPlexis Webinars

See how industry pioneers are revealing the true immune biology at each development stage

Proteomics Webinar Series

Proteomics Webinars

Explore the future of Cellular Immunotherapy

Learn how our unique technology is playing a critical part in advancing cellular immunotherapy

Discover how IsoPlexis is changing the way cell therapies are developed & manufactured

Review several publications & case studies

The Future of Cellular Immunotherapy
Matthew Hewitt, PhD, Head of R&D (a.i.) and Clinical Development, Personalized Medicine and Stacey Willard, PhD, Director of Product Management, IsoPlexis
Proteomics Webinars

Applying Single-Cell Proteomics

Proteomic and genomic insights into COVID-19

Mapping functional immune responses at the single-cell and serum level to study COVID-19

Using single-cell proteomics to study how to create a balanced and durable immune response in COVID-19 patients and assist efforts to create future vaccines and therapies

Improving COVID-19 Treatment & Vaccine Development by Modulating the Immune Response: Applying Single-Cell Proteomics
Dr. James Heath, Professor and President of Institute of Systems Biology
Proteomics Webinars

Understand the Structure and Functions of the p53 Pathway

How changes in MDM2-p53 signaling affects the timing and development of tumors

The affect of signaling networks on cancer therapy resistance

Using single-cell phosphoproteomics to identify key signaling events in glioblastoma

The Structure and Functions of the p53 Pathway
Arnold Levine, PhD, Professor Emeritus, Simons Center for Systems Biology, Institute for Advanced Study
Proteomics Webinars

Understand the role of cytokines and neuroinflammation in COVID-19 patients with neurological manifestations

Discover how neurological complications differ from traditional symptoms of COVID-19

See how understanding the pathophysiology of COVID-19 can offer more targeted treatments for neurological issues

Learn how translating this knowledge reveals sources of damage from the virus, and can help explain the immune system

Understanding the Role of Cytokines and Neuroinflammation
Shelli Farhadian, MD, PhD, Assistant Professor, Yale School of Medicine
Proteomics Webinars

Learn how single-cell functional biomarkers can help you advance your cancer therapies

The role of single-cell functional proteomics and IsoPlexis' Single-Cell Secretome solution to predict persistence in a novel combination therapy

Methods to track T cell anti-tumor activity and in vivo biodistribution

The application of single-cell functional proteomics in identifying biomarkers in next-generation therapies

 
The Role of Single-Cell Functional Biomarkers
Giuilia Parisi, PhD, Project Scientist, Department of Microbiology, Immunology and Molecular Genetics, University of California
Proteomics Webinars

Learn how to access each cell's functional biology

Visualize how each immune cell is functionally communicating & contributing to orchestrating response

Learn how functional proteomics can help you gather predictive data to accelerate your research

Explore the intuitive and powerful visualizations, powered by the automated IsoSpeak software

Accessing Functional Biology with IsoSpeak
Patrick Paczkowski, PhD, SVP of Software, IsoPlexis
Proteomics Webinars

Learn how Cancer Cell Communication can Infer a Strategy to Inhibit Tumor Cell Migration

How cell density and proliferation affect tumor cell metastasis and how they shape the development of novel therapies

How cytokine profiling and highly multiplexed proteomic analysis of three-dimensional models help identify proteins encouraging cell migration

How identifying a potential mechanism promoting tumor cell migration enables the development of a strategy to decrease tumor cell metastatic capacity

Understanding Cancer Cell Communication
Denis Wirtz, PhD, Vice Provost for Research Director, Johns Hopkins Physical Sciences-Oncology Center Johns Hopkins University and Johns Hopkins School of Medicine
Proteomics Webinars

Learn to reveal cancer resistance through single-cell intracellular proteome

Learn how functional proteomics is filling the translational gap in single-cell technology

See how IsoPlexis' single-cell proteomic data is predicting resistance in tumor cells

Discover how single-cell phosphoproteomics informs targeted combination therapies

Cancer Resistance Revealed
Rui Zheng, PhD, VP of Innovations, IsoPlexis
Proteomics Webinars

Understand the pathogenesis, the role of cytokines, and the immune response in COVID-19

Understanding and detecting immune response and how function plays a role in developing the therapies that will make a difference in COVID-19

Therapeutic strategies to overcome pathogenesis of severe inflammation

How testing and diagnosis of the immune response to infectious disease will play a role

Understanding the Pathogenesis, the Role of Cytokines, and the Immune Response in COVID-19
David Ho, MD, Scientific Director and CEO of the Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center
Proteomics Webinars

A fireside chat with IsoPlexis user Dr. Moryia Tsuji from Columbia

Using more predictive single cell proteomics in mouse models to understand correlative T cell potency in infectious disease vaccines

Understanding of more predictive T cell potency in mouse models important for understanding vaccine development

The challenges in pre-clinical vaccine development today that can be overcome by having potency tools and better ways to characterize human immune response

Dr. Moriya Tsuji – Using proteomics to enable the adaptive and innate immune response in vaccines against COVID-19
Moriya Tsuji, MD, PhD, Professor of Medicine at Aaron Diamond AIDS Research Center, Columbia University
Proteomics Webinars

Learn how rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma

Discover how a trimeric extracellular moiety of APRIL has enhanced binding to BCMA and TACI compared with monomeric APRIL when incorporated into a CAR

Explore why trimeric APRIL-based CAR are efficient against BCMA-negative multiple myeloma

Learn why T cells transduced with a trimeric APRIL-based CAR are a promising approach for the treatment of multiple myeloma

Targeting Multiple Myeloma
Andrea Schmidts, Postdoctoral Research Fellow, MD Cellular Immunotherapy Program, MGH Cancer Center and Harvard Medical School
Proteomics Webinars

Learn how single-cell functional proteomics is crucial in the informed design and development of the next generation of cell therapies

Discover how using single-cell cytokine expression can be used to functionally profile CAR-Tregs

Explore approaches to profiling and characterization of engineered immune cells to mitigate unwanted effects

Designing Next-Generation Regulatory T Cell Therapies with Single-Cell Proteomics
Leonardo Ferreira, PhD Postdoctoral Scholar University of California, San Francisco
Proteomics Webinars

Learn how discovery in cell therapy and combination therapy is benefiting from single-cell polyfunctional strength metrics

Identify the presence of small polyfunctional cell subpopulations that correlate with anti-tumor activities

Evaluate molecules that enhance the efficiency of cell therapy

Assess the effects of gene editing (CRISPR) on response in model systems

Single-Cell Polyfunctional Strength Applied to Cell Engineering & Therapy Discovery
Jon Chen, MS, Director, New Collaborators
Proteomics Webinars

Discover biomarkers that could elucidate the mechanism of various autoimmune disorders as well as autoimmune and inflammatory reactions to immunotherapies

Explore IsoPlexis’ advanced immune-based approaches in systemic lupus erythematosus and adverse events like cytokine release syndrome and neurotoxicity in cell therapy

Determine correlates and drivers of adverse reactions using single-cell functional proteomics

Learn how these biomarkers may improve therapeutic development and intervention

Novel Single-Cell Biomarker Strategies for Autoimmune Disease and Adverse Events in Immunotherapy
Dr. Rong Fan, Yale University
Proteomics Webinars

Uncover strategies to improve T-cell function in the TME, and Polyfunctional Strength Index (PSI) concerning a range of TME immunotherapy challenges

Improve T-cell functionality for adoptive T cell therapy in metastatic colon cancer using small-molecule strategies

Use PSI to Unlock key insights into how the immune system can be modulated to improve development and solid tumor immunotherapeutic strategies

Discover novel correlative single-cell data from T-cells from the blood of colon cancer patients

Improving T-cell Function in the Solid Tumor Microenvironment using Advanced Immunotherapeutic Strategies
Dr. Sruthi Ravindranathan, Post Doctoral Researcher in the Waller Lab at Winship Cancer Institute of Emory University
Proteomics Webinars

Explore an overview of current biomarker strategies for guiding the use of combination checkpoint immunotherapies in blood cancers

Review advanced immune-based approaches in acute myeloid leukemia that combine chemotherapy with checkpoint therapy

Explore relevant biomarker strategies associated with these approaches

See how single-cell cytokine analysis system and PSI demonstrate that specific cytokine potency contributors correlate with overall survival

Biomarker Strategies for Optimizing Checkpoint Immunotherapy Treatment
Dr. Naval Daver, Associate Professor, Department of Leukemia, MD Anderson Cancer Center
Proteomics Webinars

Discover how polyfunctional strength is making an impact with bispecifics and combination checkpoint therapies

Evaluate T cell responses induced by various bispecific T cell engagers across phenotypes

Understand the heterogeneity of TIL polyfunctionality in solid tumors in response to checkpoint inhibitors

Uniquely correlate clinical anti-tumor responses with IsoPlexis data

Optimize combination cancer vaccines in melanoma using model systems

Single-Cell Polyfunctional Strength Applied to Checkpoint & Antibody Based Immunotherapies
Will Singleterry, PhD, Director of Business Development, IsoPlexis
Proteomics Webinars

Understand how new innate & myeloid single cell functional profiling is uncovering drivers of inflammatory disease

Discover the impact of therapy on MS by tracking inflammatory polyfunctionality in monocytes

Uncover NK contribution to Crohn's disease through proinflammatory polyfunctionality

Reveal the striking heterogeneity of polyfunctionality in PMF patient granulocytes suggesting directions for therapy in MPNA

Single-Cell Polyfunctional Strength Applied to Innate & Myeloid Research
Jens Eberlein, PhD, Senior Field Application Scientist, IsoPlexis
Proteomics Webinars

Discover the evolution of the cell therapy industry and how IsoPlexis is redefining what's possible through the ability to stratify patient response to novel immunotherapy regimens

Explore how cytokines reveal function in immunotherapy and the challenges in revealing mechanism & responders through blood cytokines & phenotype

Reveal highly polyfunctional immune cells that correlate to in-vivo response to immunotherapy

Uncover potent cytokine mechanism using Single-Cell PSI to reveal responders in trials with checkpoint inhibitors

Better by Design: Single-Cell Characterization for Enhanced Cell Therapies
Dr. James Heath, Professor and President of the Institute of System Biology

Technology Webinar Series

Technology Webinars

Learn how to reveal unique functional biology with Single-Cell Secretome

See how our unique products are shaping the future of immune medicine

Learn how functional proteomics is filling the translational gap in single-cell

Review related published studies and articles

Unique Functional Biology Revealed
Jon Chen, MS, Technology Co-Inventor, IsoPlexis
Technology Webinars

Learn how to reveal functional biology from monocytes & myeloid cells

Explore three cases that reveal true functional biology from innate and myeloid cells with the IsoPlexis Innate Immune solution

Learn the principles behind IsoCode and CodePlex technology

Explore powerful visualizations available on the automated IsoSpeak Software

New Functional Biology Revealed from Monocytes and Other Innate & Myeloid Cells
Cynthia Turcotte, PhD, Senior Director of Applications, IsoPlexis
Technology Webinars

Learn how to uncover your functional biology with IsoU

Understand how our unique IsoCode Single-Cell Technology reveals True Functional Phenotype

Explore the wide range of applications available in IsoCode and CodePlex Chip families

Discover IsoSpeak's powerful visualizations and push-button informatics

Uncover Your Functional Biology Using IsoU
Stacey Willard, PhD, Product Manager, IsoPlexis
Technology Webinars

Learn to apply next-generation CodePlex to accelerate workflows

Understand how to apply CodePlex Secretome to accelerate proteomic workflows

Learn how to the new CodePlex Secretome solution uses one system for a faster approach with significantly less sample volume

See how the CodePlex Scretome helps you obtain highly multiplexed cytokine data

CodePlex Secretome: Learn to Apply Next Generation CodePlex to Accelerate Workflows
Jon Chen, Technology Co-Inventor, IsoPlexis
Technology Webinars

Learn how to automate your entire multiplexed ELISA workflow to increase work-away time

Increase your work-away time by up to 80x with a completely automated highly multiplexed ELISA workflow requiring only five minutes of hands-on time

Use up to 10x smaller sample volumes to generate complete highly multiplexed ELISA data

Easily operate only one instrument, unlike traditional workflows which require numerous instrumentation

Automate Your Entire Multiplexed Elisa Workflow to Increase Work-Away Time
Damini Patel, Field Application Scientist, IsoPlexis
Technology Webinars

Discover how to navigate IsoSpeak’s powerful visualizations of the single-cell data you need to correlate with outcomes

Access a unique collection of predeveloped tools to see the data at multiple levels

Adjust all views in real time based on user input

Explore complex single-cell datasets with novel, customized analytics

Streamline reporting with publication quality graphs and data exporting

Getting started with IsoSpeak Single-Cell Software: Advanced Visualizations to Enable Insights
Patrick Paczkowski, PhD, VP of Software, IsoPlexis
Technology Webinars

Walk through how the IsoLight system automates single cell data generation for analysis and visualization in IsoSpeak

Load prepared samples into preconfigured assay chips

Walk away chip processing, including cell separation, incubation, cell imaging and proteomic scanning

Parallel data generation for up to 8 samples per run

Export raw data merged with chip configuration info directly for data processing in IsoSpeak software

Getting started with the IsoLight System: How it works to automate your workflow and get you data
Peter Tsiompilkas, MS, VP or Product R&D, IsoPlexis
Technology Webinars

Learn how the sample preparation protocols simplify the process of getting the most out of every sample

Access a portfolio of predeveloped and validated protocols for enrichment and stimulation

Reduce development time and precious sample usage needed to get going

Customize protocols moving forward by tapping into IsoPlexis' assay development resources

Getting started with Sample Preparation on the IsoLight System: CAR-T project example
Jens Eberlein, PhD, Senior Field Application Scientist, IsoPlexis