IsoPlexis Webinars

See how industry pioneers are revealing the true immune biology at each development stage

Single-Cell Webinar Series

Single-Cell Webinars

A fireside chat with IsoPlexis user Dr. Moryia Tsuji from Columbia

Using more predictive single cell proteomics in mouse models to understand correlative T cell potency in infectious disease vaccines

Understanding of more predictive T cell potency in mouse models important for understanding vaccine development

The challenges in pre-clinical vaccine development today that can be overcome by having potency tools and better ways to characterize human immune response

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Dr. Moriya Tsuji

Single-Cell Webinars

Learn how rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma

Discover how a trimeric extracellular moiety of APRIL has enhanced binding to BCMA and TACI compared with monomeric APRIL when incorporated into a CAR

Explore why trimeric APRIL-based CAR are efficient against BCMA-negative multiple myeloma

Learn why T cells transduced with a trimeric APRIL-based CAR are a promising approach for the treatment of multiple myeloma

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Andrea Schmidts, Postdoctoral Research Fellow, MD Cellular Immunotherapy Program, MGH Cancer Center and Harvard Medical School

Single-Cell Webinars

Learn how single-cell functional proteomics is crucial in the informed design and development of the next generation of cell therapies

Discover how using single-cell cytokine expression can be used to functionally profile CAR-Tregs

Explore approaches to profiling and characterization of engineered immune cells to mitigate unwanted effects

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Designing Next-Generation Regulatory T Cell Therapies with Single-Cell Proteomics

Leonardo Ferreira, PhD Postdoctoral Scholar University of California, San Francisco

Single-Cell Webinars

Learn how discovery in cell therapy and combination therapy is benefiting from single-cell polyfunctional strength metrics

Identify the presence of small polyfunctional cell subpopulations that correlate with anti-tumor activities

Evaluate molecules that enhance the efficiency of cell therapy

Assess the effects of gene editing (CRISPR) on response in model systems

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Single-Cell Polyfunctional Strength Applied to Cell Engineering & Therapy Discovery

Jon Chen, MS, Director, New Collaborators

Single-Cell Webinars

Discover biomarkers that could elucidate the mechanism of various autoimmune disorders as well as autoimmune and inflammatory reactions to immunotherapies

Explore IsoPlexis’ advanced immune-based approaches in systemic lupus erythematosus and adverse events like cytokine release syndrome and neurotoxicity in cell therapy

Determine correlates and drivers of adverse reactions using single-cell functional proteomics

Learn how these biomarkers may improve therapeutic development and intervention

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Novel Single-Cell Biomarker Strategies for Autoimmune Disease and Adverse Events in Immunotherapy

Dr. Rong Fan, Yale University

Single-Cell Webinars

Uncover strategies to improve T-cell function in the TME, and Polyfunctional Strength Index (PSI) concerning a range of TME immunotherapy challenges

Improve T-cell functionality for adoptive T cell therapy in metastatic colon cancer using small-molecule strategies

Use PSI to Unlock key insights into how the immune system can be modulated to improve development and solid tumor immunotherapeutic strategies

Discover novel correlative single-cell data from T-cells from the blood of colon cancer patients

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Improving T-cell Function in the Solid Tumor Microenvironment using Advanced Immunotherapeutic Strategies

Dr. Sruthi Ravindranathan, Post Doctoral Researcher in the Waller Lab at Winship Cancer Institute of Emory University

Single-Cell Webinars

Explore an overview of current biomarker strategies for guiding the use of combination checkpoint immunotherapies in blood cancers

Review advanced immune-based approaches in acute myeloid leukemia that combine chemotherapy with checkpoint therapy

Explore relevant biomarker strategies associated with these approaches

See how single-cell cytokine analysis system and PSI demonstrate that specific cytokine potency contributors correlate with overall survival

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Biomarker Strategies for Optimizing Checkpoint Immunotherapy Treatment

Dr. Naval Daver, Associate Professor, Department of Leukemia, MD Anderson Cancer Center

Single-Cell Webinars

Discover how polyfunctional strength is making an impact with bispecifics and combination checkpoint therapies

Evaluate T cell responses induced by various bispecific T cell engagers across phenotypes

Understand the heterogeneity of TIL polyfunctionality in solid tumors in response to checkpoint inhibitors

Uniquely correlate clinical anti-tumor responses with IsoPlexis data

Optimize combination cancer vaccines in melanoma using model systems

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Single-Cell Polyfunctional Strength Applied to Checkpoint & Antibody Based Immunotherapies

Will Singleterry, PhD, Director of Business Development, IsoPlexis

Single-Cell Webinars

Understand how new innate & myeloid single cell functional profiling is uncovering drivers of inflammatory disease

Discover the impact of therapy on MS by tracking inflammatory polyfunctionality in monocytes

Uncover NK contribution to Crohn's disease through proinflammatory polyfunctionality

Reveal the striking heterogeneity of polyfunctionality in PMF patient granulocytes suggesting directions for therapy in MPNA

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Single-Cell Polyfunctional Strength Applied to Innate & Myeloid Research

Jens Eberlein, PhD, Senior Field Application Scientist, IsoPlexis

Single-Cell Webinars

Discover the evolution of the cell therapy industry and how IsoPlexis is redefining what's possible through the ability to stratify patient response to novel immunotherapy regimens

Explore how cytokines reveal function in immunotherapy and the challenges in revealing mechanism & responders through blood cytokines & phenotype

Reveal highly polyfunctional immune cells that correlate to in-vivo response to immunotherapy

Uncover potent cytokine mechanism using Single-Cell PSI to reveal responders in trials with checkpoint inhibitors

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Better by Design: Single-Cell Characterization for Enhanced Cell Therapies

Dr. James Heath, Professor and President of the Institute of System Biology

Technology Webinar Series

Technology Webinars

Discover how to navigate IsoSpeak’s powerful visualizations of the single-cell data you need to correlate with outcomes

Access a unique collection of predeveloped tools to see the data at multiple levels

Adjust all views in real time based on user input

Explore complex single-cell datasets with novel, customized analytics

Streamline reporting with publication quality graphs and data exporting

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Getting started with IsoSpeak Single-Cell Software: Advanced Visualizations to Enable Insights

Patrick Paczkowski, PhD, VP of Software, IsoPlexis

Technology Webinars

Walk through how the IsoLight system automates single cell data generation for analysis and visualization in IsoSpeak

Load prepared samples into preconfigured assay chips

Walk away chip processing, including cell separation, incubation, cell imaging and proteomic scanning

Parallel data generation for up to 8 samples per run

Export raw data merged with chip configuration info directly for data processing in IsoSpeak software

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Getting started with the IsoLight System: How it works to automate your workflow and get you data

Peter Tsiompilkas, MS, VP or Product R&D, IsoPlexis

Technology Webinars

Learn how the sample preparation protocols simplify the process of getting the most out of every sample

Access a portfolio of predeveloped and validated protocols for enrichment and stimulation

Reduce development time and precious sample usage needed to get going

Customize protocols moving forward by tapping into IsoPlexis' assay development resources

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Getting started with Sample Preparation on the IsoLight System: CAR-T project example

Jens Eberlein, PhD, Senior Field Application Scientist, IsoPlexis