Targeting Autoimmune Progression
Solutions Accelerated by IsoPlexis
- Systemic Lupus Progression
T Cell polyfunctional subsets in SLE determine contribution to pathogenesis and potential targets1
Uncover the functional immune subsets which drive progression in autoimmune diseases.
Identify differences & mechanism in the expanded T cell populations within autoimmune disease
Polyfunctionality reveals key Tfh subsets that lead to disease progression in SLE
SLE patients exhibit polyfunctional Tfh with B-helper cytokine IL-21 and effector cytokines IL-2, IFNγ and TNFα, indicating potential therapeutic targets based on source of disease progression