We are revealing true functional immune biology, unlocking development, and accelerating biomarker discovery. Our automated suite of life sciences products are built to power the future, which lies in immune medicines.
Adaptive Immune
A fully automated solution for single-cell functional phenotyping of immune cells.
Innate Immune
Single-cell functional phenotyping for innate & myeloid cell types, automated on the IsoLight System.
Inflammation
Reveal the functional sources of inflammation from rare polyfunctional subsets of cells in an automated manner.
Intracellular Proteome
Measure cellular protein to protein interactions and adaptive resistance pathways. Available Late 2020.
Run an entire multiplexed ELISA workflow in a completely automated and hands-off manner.
Harnessing the power of functional proteomics with the IsoLight™.
- Effector
Granzyme B, IFN-γ, MIP-1α, Perforin, TNF-α, TNF-β
- Stimulatory
GM-CSF, IL-2, IL-5, IL-7, IL-8, IL-9, IL-12, IL-15, IL-21
- Chemoattractive
CCL11, IP-10, MIP-1β, RANTES
- Regulatory
IL-4, IL-10, IL-13, IL-22, TGFβ1, sCD137, sCD40L
- Inflammatory
IL-1β, IL-6, IL-17A, IL-17F, MCP-1, MCP-4
- Effector
Granzyme B, IFN-γ, MIP-1α, TNF-α
- Stimulatory
GM-CSF, IL-2, IL-5, IL-7, IL-12p70, IL-15, IL-18, IL-21, sCD137
- Chemoattractive
CCL11, CXCL1, CXCL13, IP-10, RANTES
- Regulatory
Fas, IL-4, IL-10, IL-13, IL-27, TGFβ1
- Inflammatory
IL-6, IL-17A, MCP-1, IL-1β
- Membrane Stain
- Memory T cell subsets
- Effector
IFN-γ, MIP-1α, TNF-α, TNF-β
- Stimulatory
GM-CSF, IL-8, IL-9, IL-15, IL-18, TGF-α, IL-5
- Chemoattractive
CCL11, IP-10, MIP-1β, RANTES, BCA-1
- Regulatory
IL-10, IL-13, IL-22, sCD40L
- Inflammatory
IL-1β, IL-6, IL-12-p40, IL-12, IL-17A, IL-17F, MCP-1, MCP-4, MIF
- Growth Factors
EGF, PDGF-BB, VEGF
- Membrane Stain
- Th1 Pro-inflammatory
GM-CSF, IFN-γ, IL-2, IL-12, TNF-α, TNF-β
- Th2 Pro-inflammatory
IL-4, IL-5, IL-7, IL-9, IL-13
- Chemoattractive
CCL11, IL-8, IP-10, MCP-1, MCP-4, MIP-1α, MIP-1β, RANTES
- Regulatory
IL-10, IL-15, IL-22, TGF-β1
- Th17 Pro-inflammatory
IL-1β, IL-6, IL-17A, IL-17F, IL-21
- Cytolytic
Granzyme B, Perforin
- Other
sCD40L, sCD137
- Membrane Stain
- Memory T cell subsets
P-PRAS40, P-IkBα, P-NF-kβ p65, P-Met, P-p44/42 MAPK, P-S6 Ribosomal, P-Rb, P-p90RSK, P-STAT3, P-MEK1/2, P-Stat1, P-Stat5, P-eIF4E, Cleaved PARP, Alpha Tubulin
P-Akt, P-p53, P-PD1, P-LCK, P-CD3 zeta, P-Zap70, P-CCR7, P-CD28, P-41BB, P-MEK 1/2, P-P44/42 MAPK (ERK1/2), P-Jak1, P-Jak2, P-AMPK, P-PI3K, P-mTOR, P-P21, P-LAT, P-NF-kB p65, Alpha Tubulin
Granzyme B, IFN-y, MIP-1a, Perforin, TNF-a, TNF-B, GM-CSF, IL-2, IL-5, IL-7, IL-8, IL-9, IL-12, IL-15, IL-21, CCL11, IP-10, MIP-1B, RANTES, IL-4, IL-10, IL-13, IL-22, TGF-B1, sCD137, sCD40L, IL-1B, IL-6, IL-17a, IL17F, MCP1, MCP-4, IL-18, TGF-a, BCA-1, IL-12-p40, MIF, EGF, PDGF-BB, VEGF
IL-17A, TGF-b1, MIP-1a, IL-9, MIP-1b, IL-6, IL-7, IL-8, IFN-y, IP-10, GM-CSF, IL-4, IL-5, IL-10, TNF-a, MCP-1, IL-13, IL-2, Perforin, sCD137, TNF-b, Granzyme B, IL-15
IL-1b, IL-2, IL-4, IL-6, IL-7, IL-10, IL-12, IL-13, IL-17, MCP-1, GM-CSF, MIP-1a, MIP-1b, TNF-a, IFN-y
IL-17A, TGF-b1, MIP-1a, MIP-1b, IL-6, IL-8, IFN-y, GM-CSF, IL-4, IL-10, TNF-a, MCP-1, IL-2, IL-15, Rantes (MPN), IL1a, IL1b, IL12, CCL2, CXCL5 * (MPN)
IL-17A, TGF-b1, MIP-1a, MIP-1b, IL-6, IL-7, IL-8, IFN-y, IP-10, GM-CSF, IL-4, IL-5, IL-10, TNF-a, MCP-1, IL-2, Perforin, sCD40L, sCD137, TNF-b, Granzyme B, IL-15, PDGF-BB
IL-6, IL-7, IFN-y, IL-4, IL-5, IL-10, TNF-a, MCP-1, IL-13, IL-2, EGF, PDGF-BB, VEGF, Rantes (MPN), MIF, FGF, HGF, IL1a, IL1b, IL12
P-PRAS40, P-IkBα, P-NF-kβ p65, P-Met, P-p44/42 MAPK, P-S6 Ribosomal, P-Rb, P-p90RSK, P-STAT3, P-MEK1/2, P-Stat1, P-Stat5, P-eIF4E, Cleaved PARP, Alpha Tubulin
Adaptive Immune Panel (Coming Soon)
P-Akt, P-p53, P-PD1, P-LCK, P-CD3 zeta, P-Zap70, P-CCR7, P-CD28, P-41BB, P-MEK 1/2, P-P44/42 MAPK (ERK1/2), P-Jak1, P-Jak2, P-AMPK, P-PI3K, P-mTOR, P-P21, P-LAT, P-NF-kB p65, Alpha Tubulin
