Assessing Functional Quality of Single TILs for Correlative Immunotherapy Biomarkers

Application Note

Assessing Functional Quality of Single TILs for Correlative Immunotherapy Biomarkers

Learn how using Single-Cell PSI helps you reveal mechanisms in the Tumor Microenvironment.

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What's Inside

In this Application Note we discuss:

Highlight the challenges in functional characterization of TILs in checkpoint and combination therapies

Describe the workflow for functional single-cell analysis from both solid tumor TILs as well as patient PBMC

Predict patient response to checkpoint therapy using PSI as a biomarker in solid tumor TILs, as well as correlate response from these solid tumor TILs with PSI from peripheral blood

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A Deeper Look

More about this Application Note

Overcoming Challenges in Checkpoint Combination Therapies

Checkpoint inhibitor blockade therapy has rapidly advanced and is now established as a powerful way to manage various malignant tumors.

Despite the promising outcomes, there are a significant number of patients who do not respond to these immunotherapies.

Download this App Note to learn how IsoPlexis’ PSI helps you overcome these challenges with a wide range of applications in checkpoint and combination therapy research.

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