Cracking the IsoCode: Single Cell Functional Biomarkers Challenge

What will you uncover through Single-cell Functional Proteomics?

IsoPlexis announces the launch of Cracking the IsoCode: Single Cell Functional Biomarkers Challenge. Researchers are invited to share next generation insights using single-cell functional proteomics for the opportunity to win a project on the IsoLight system at your institution (IsoCode Kit, Advanced Analysis Support, Experimental Design and consultation).

isocode chip

Completing the puzzle with single cell functional proteomics: True functional immune biology

RNA-seq, histology, and flow cytometry have proven critical for tumor analyses and various mutational and location-based metrics. However, a true functional definition of immune fitness and function of each single cell is required to complete this puzzle to confirm how each immune cell is performing to discover robust correlations with response. IsoPlexis is addressing this critical need and completing the puzzle as a new standard for functional cytokine immune profiling at the single-cell level.

Reveal Unique Correlates with Single Cell Functional Proteomics

IsoPlexis’ platform is the only source of this true functional profiling information, and overcomes the three challenges that exist today by:
  • Detecting the specific cytokines (over 30) that each single immune cell is secreting
  • Identifying the unique highly polyfunctional (secreting multiple cytokines simultaneously) subsets within a cell sample that are driving response, directly from the cytokine-based proteome of each cell
  • Characterizing true secretions per cell, thus defining correlative immune function, fitness, and potency of single cells
Using these metrics, IsoPlexis has generated data that has correlated with clinical outcomes in multiple studies, side by side, when legacy technologies such as flow cytometry and bulk ELISA have not. The proof is in the data: with true in vivo correlates, IsoPlexis’ technology is completing the puzzle in what is occurring within your therapies, so why wait? See how your cells are truly functioning.

Cracking the IsoCode: Challenge Details

Submit an abstract (up to 500 words) proposing a project that uses the IsoLight platform and IsoCode solution. Specify the sample types, number of samples, and include your plans for data analysis using the IsoSpeak software solution. A Cracking the IsoCode Challege committee will review the proposals and select winners based on research novelty and innovation. Two winners will be selected and each will be awarded 12 free IsoCode chips (one 8 chip kit, one 4 chip kit), along with advanced analysis support, and experimental design consultation from IsoPlexis. Enter your abstract starting Nov 20, 2019 and before Dec 31, 2019. Projects proposed should have at least 12 samples and experiments must be completed before Jan 31, 2020. Please contact us at [email protected] if you have any additional questions. See Terms & Conditions for contest rules and eligibility.

Submit Your Abstract

The submission deadline has now passed.