IsoPlexis has partnered with the Institute for Systems Biology (ISB) to map functional immune responses at the single cell level to study COVID-19. Uncovering functional immune responses using IsoPlexis technologies have underpinned key breakthroughs in therapies that harness the immune system across disease areas. The data from this partnership will be released as soon as possible and made globally available to researchers combating the disease. Research will be performed on immune cells from individuals who have been diagnosed with or recovered from COVID-19. IsoPlexis' single cell functional proteomics platform will be utilized on a variety of immune cell types, including various T cells and myeloid cells to put together a map of the overall response.
In a partnership with the Division of Infectious Diseases, Department of Medicine at Columbia University, IsoPlexis' Single-Cell Secretome immune profiling solutions will be used to study cellular drivers of durable and protective immune response to COVID-19. T cell and other immune cell polyfunctional cytokine responses on IsoPlexis' platform have previously shown to be predictive of a variety of responses in human and mice studies throughout cancer immunology and infectious disease. Additionally, Dr. Moriya Tsuji, Professor of Medicine at Columbia University, has published vaccine studies identifying protective immune response in malaria and in oncology, using IsoPlexis' single-cell functional proteomics platform. The overall goal is to continue to detect and discover critical components in the overall cellular response to COVID-19, which can then be used to speed much needed therapies.