Sean Mackay
Chief Executive Officer & Co-Founder + Director

Sean is an experienced entrepreneur at the convergence of life sciences and healthcare delivery. He co-founded and leads IsoPlexis, a venture-backed life science startup developing a diagnostic system to measure cellular immune response in patients. Sean led IsoPlexis through foundational licensing and capital raising, while building the team and developing applications and product. Previously, Sean advanced business development at Kleiner Perkins-backed and incubated Lifesquare, which connected patients, payers, and providers through sharing essential healthcare information. While at Lifesquare, Sean generated strategic initiatives related to partnerships across the healthcare ecosystem. Through work at Lazard and several early-stage ventures, he developed deep experience in structuring and financing life sciences companies. Sean advised multiple biotechnology and medical technology companies on how to manage times of strategic change. He founded life science-focused debt advisory business line at Lazard, helping grow revenues ten-fold for the group and establishing infrastructure and hiring required to sustain the business. Sean graduated with a BS in Economics from the University of Pennsylvania’s Wharton School and an MBA from the Yale School of Management.