The IsoCode Chip (SCBC) system captures the omic, or full, end function from thousands of single cells in parallel to better understand complex patient response. The system, recognized in the literature as the SCBC, has been well validated in various immune and cancer detection applications. For proteomic applications, it uses rigorous quantitation of ELISA antibody based capture, applied to single cell detection. Control of strict specificity, sensitivity, and variability provides the ability to compare across large groups of patients.
Mapping each cell's full function reveals powerful cell subsets. The IsoCode system uses its ability to detect full, omic function per cell to find subsets of cells that help determine objective patient response.
See Cancer Discovery for applying IsoCode Chip (SCBC) single-cell secretomic cytokine profiling to earlier understanding of cell immunotherapy patient responses.
secretomics: TCR T-Cell and CAR T-Cell immuno-therapy personalized medicine
phosphoproteomics: improving predictive profiling of solid tumor glioblastoma
secretomics: uncovering patient biomarkers in lupus (auto-immune disease)
metabolomics: monitoring energy transfer and consumption in cancer for new biomarkers
secretomics: uncovering patient biomarkers in inflammatory cancers (myelofibrosis)